Leucoderma and Melanoderma

Leucoderma

Leucoderma in early syphilis.

CASE 1 A 25-year-old man first noticed depigmented lesions on the face and neck; a few days later he developed asymptomatic erythematous papular and scaly lesions over the trunk and extremities, and moist papular lesions on the scrotal skin. Two weeks later when he reported to us, some of the trunk lesions had also become depigmented. Four months earlier after an extramarital sexual exposure, t...

Treatment for Leucoderma

A Case of Syphilitic Melanoderma

A Hindu male, unmarried, pujari by profession, was admitted into the Thomason Hospital, Agra, on 13th September, 1941, with the-following complaints :? (i) Pigmentation of the skin all over the body. (ii) Burning sensation all over the body. The patient stated that three years back he noticed a black patch on the palm of the right hand which slowly extended above the wrist. Within two years all...

Diagnosis: Melanoderma after Hematopoietic Stem Cell Transplantation

Figure 2. A) Skin. A slight perivascular infiltration of mononuclear inflammatory cells and dermal melanophages (arrows) are seen (HEx200). B) An increment in melanin pigment in basal keratinocytes (arrow heads) and dermal melanophages (white arrows) are highlighted by Fontana-Masson stain (x200). Figure 1. Patchy melanoderma lesions mimicking ecchymoses in the legs, trunk.